DESCRIPTION:
ALPHAGAN™ is an alpha adrenergic receptor agonist with high degree of selectivity to alpha, receptors. It has a peak ocular hypotensive effect occuring at two hours post-dosing

Each mL contains:
Brimonidine Tartrate 2 mg equivalent to Brimonidine         1.3 mg
Benzalkonium Chloride IPNSNF                                              0.05 mg
Purified Water IP                                                                           q.s.

INDICATIONS AND USAGE:
ALPHAGAN™ is indicated for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension. The IOP lowering effect of ALPHAGAN™ ophthalmic solution diminishes over time in some patients. The loss of effect appears with a variable time of onset in each patient and should be closely monitored.

DOSAGE AND ADMINISTRATION:
The recommended dose is one drop of ALPHAGAN™in the affected eye(s) two times daily. For those patients whose IOP peaks in the afternoon or need additional IOP control, an additional drop of brimonidine in the aftemoon can be added.

HOW SUPPLIED:
ALPHAGAN™ ophthalmic solution is supplied in 5 mL sterile white opaque plastic dropper bottle.